MOTS-C

MOTS-C is a mitochondrial-derived peptide composed of 16 amino acids encoded by the mitochondrial 12S rRNA region. It plays a significant role as a metabolic regulator, promoting insulin sensitivity, preventing obesity, enhancing muscle and bone metabolism, modulating immune responses, and delaying aging processes. MOTS-C exerts its effects primarily through activation of the AICAR-AMPK signaling pathway and regulates metabolic genes like GLUT4, STAT3, and IL-10.

Research involving MOTS-C commonly explores:

• Reduction of insulin resistance and prevention of metabolic disorders such as type 2 diabetes and obesity.
• Improvement of muscle function and bone metabolism, with potential applications in muscular dystrophies and osteoporosis.
• Immune regulation by modulating T cell function and inflammatory cytokine balance, with implications for autoimmune diseases and infection resistance.
• Anti-aging properties through metabolic homeostasis maintenance and oxidative stress reduction.
• Potential therapeutic effects in cardiovascular diseases, inflammation-related disorders, and neurodegenerative conditions.
MOTS-C is provided as a lyophilized peptide powder for laboratory research use only (RUO) and is not approved for clinical, diagnostic, or therapeutic use in humans or animals.

Product details:

• Synonyms: MOTS-c, mitochondrial open reading frame of the 12S rRNA-c
• Purity: ≥98%
• Molecular Weight: Approximately 2410 Da (varies by source)
• Appearance: White to off-white lyophilized powder

This product is intended exclusively for scientific research and laboratory investigation in compliance with regulatory guidelines.