Pangragon (Pancragen)

Pangragon (Pancragen) is a synthetic tetrapeptide with the amino acid sequence Lys-Glu-Asp-Trp (KEDW), developed as a bioregulator peptide primarily studied in cellular, metabolic, and pancreatic research models. It is identified for its potential ability to modulate pancreatic cell function, metabolic enzyme activity, and anti-inflammatory responses, making it a promising candidate for research into pancreatic integrity, glucose metabolism, and age-related metabolic conditions.

Research involving Pangragon commonly explores:

• Regulation of pancreatic enzymatic activities influencing glucose and lipid metabolism.
• Promotion of pancreatic cell resilience, proliferation, and functional restoration, particularly targeting insulin-producing β cells and glucagon-producing α cells.
• Anti-inflammatory and anti-apoptotic activities reducing proapoptotic markers (e.g., p53) and enhancing antiapoptotic proteins (e.g., Mcl1).
• Modulation of cellular aging biomarkers and epigenetic gene expression impacting metabolic homeostasis.
• Enhancement of cellular communication relevant to metabolic adaptability and resilience.
Pangragon is provided as a lyophilized powder for laboratory research use only (RUO). It is not intended for diagnostic, therapeutic, or clinical use and must not be used in humans or animals.

Product details:

• Synonyms: Pancragen, KEDW peptide, pancreatic bioregulator peptide
• Purity: ≥98%
• Molecular Formula: C30H50N10O15
• Molecular Weight: Approximately 687 Da
• Amino Acid Sequence: Lys-Glu-Asp-Trp
• Appearance: White to off-white lyophilized powder

This product is intended exclusively for scientific research and laboratory investigation in compliance with applicable regulatory guidelines.