Pinealon 10 MG

Pinealon is a short synthetic tripeptide with the sequence Glu-Asp-Arg (EDR), primarily studied for its neuroprotective and anti-apoptotic properties.

Regarding its pharmacokinetics and stability:

• Pinealon’s small size and simple structure contribute to good tissue penetration and the potential ability to cross biological barriers such as the blood-brain barrier and cellular membranes.
• Research suggests that Pinealon exhibits relatively high stability in biological systems compared to longer peptides, attributed in part to its compact size and resistance to rapid enzymatic degradation.
• Studies implicate that it may have a longer half-life in plasma relative to other peptides, though detailed pharmacokinetic parameters such as exact plasma half-life have limited published data.
• Its neuroprotective effects are believed to be mediated by modulation of oxidative stress pathways (e.g., reduction of reactive oxygen species) and intracellular signaling cascades like the MAPK/ERK pathway, which may contribute to its functional stability at the cellular level.
• Molecular docking studies indicate a stable interaction with DNA sequences, suggesting a possible role in influencing gene expression related to serotonin synthesis, indirectly supporting sustained biological activity.
Pinealon is supplied as a high-purity lyophilized powder for research use only (RUO) and is not approved for human or clinical use.

Product details:

• Amino Acid Sequence: Glu-Asp-Arg (EDR)
• Molecular Weight: Approximately 418.4 Da
• Appearance: White to off-white lyophilized powder
• Known for: Neuroprotection, anti-apoptotic activity, oxidative stress reduction

Overall, Pinealon’s favorable stability and penetration properties make it a promising candidate for research into neuroprotection and cellular aging mechanisms.