5-Amino-1MQ

5-Amino-1MQ is a synthetic small molecule derivative structurally related to nicotinamide phosphoribosyltransferase (NAMPT) pathway inhibitors. It has been developed as a stabilized analog for research purposes and is primarily studied in laboratory settings for its potential effects on nicotinamide metabolism, NAD+ biosynthesis modulation and methyltransferase enzyme inhibition. Preclinical studies have investigated 5-Amino-1MQ in relation to experimental models of obesity, metabolic dysfunction and cellular energy regulation.

Research involving 5-Amino-1MQ commonly explores:

• Its role in modulating the nicotinamide N-methyltransferase (NNMT) pathway and influencing NAD+ salvage cycle activity.
• Possible contributions to metabolic regulation studies, including adiposity, lipid metabolism and insulin sensitivity.
• Experimental promotion of mitochondrial function, cellular energetics and NAD+/NADH balance in preclinical models.
• Its activity in studies of fat mass reduction, weight management and metabolic health, where its small‑molecule inhibition of NNMT is a topic of interest.
5-Amino-1MQ is provided as a lyophilized powder for laboratory research use only (RUO). It is not intended for diagnostic, therapeutic or clinical applications and must not be used in humans or animals.

Product details:

• Synonyms: 5-Amino-1-methylquinolin-1-ium, 1-Methylquinolin-5-amine
• Purity: ≥ 98%
• CAS Number: 1159580-74-0
• Molecular Formula: C10H10N2
• Molecular Weight: 158.20 Da
• Appearance: Orange lyophilized powder