VIP

Vasoactive Intestinal Peptide (VIP) is a synthetic 28-amino-acid neuropeptide known for its potent vasodilatory, immunomodulatory, and anti-inflammatory properties. It is widely studied in research for its regulatory effects on neuronal, epithelial, endocrine, and immune cell functions, particularly within the gastrointestinal, respiratory, reproductive, and cardiovascular systems.

Research involving VIP commonly explores:

• Its role in vasodilation, regulation of gastric acid secretion, and modulation of gastrointestinal motility.
• Effects on enhancing glucose-dependent insulin secretion through VPAC2 receptor activation and promoting islet β-cell proliferation.
• Modulation of immune responses, including suppression of inflammatory cytokines, promotion of anti-inflammatory cytokines, and regulation of T cell activity in autoimmune and inflammatory conditions.
• Potential therapeutic applications in inflammatory bowel disease, diabetes, rheumatoid arthritis, pulmonary hypertension, sarcoidosis, and certain cancers.
• Use of stable VIP analogs and novel delivery systems to overcome rapid degradation and broaden therapeutic potential.
VIP is provided as a lyophilized powder for laboratory research use only (RUO). It is not intended for diagnostic, therapeutic, or clinical use and must not be administered to humans or animals.

Product details:

• Synonyms: VIP, Vasoactive Intestinal Peptide
• Purity: ≥98%
• Molecular Formula: C134H225N39O41S2
• Molecular Weight: Approximately 3326 Da
• Amino Acid Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Val-His-Asn-Phe
• Appearance: White to off-white lyophilized powder

This product is intended exclusively for scientific research and laboratory investigation in compliance with applicable regulatory guidelines.